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Impaired response or insufficient dosage? – examining the potential causes of ”inadequate response” to allopurinol in the treatment of gout

OBJECTIVES: Gout is one of the most common forms of arthritis. It is well established that urate lowering therapy that aims for a serum urate less than at least 0.36mmol/l (6mg/dL) is required for successful management of gout. Allopurinol, a xanthine oxidase (XO) inhibitor is the most commonly used...

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Détails bibliographiques
Publié dans:Semin Arthritis Rheum
Auteurs principaux: Stamp, Lisa K, Merriman, Tony R, Barclay, Murray L, Singh, Jasvinder A, Roberts, Rebecca L, Wright, Daniel FB, Dalbeth, Nicola
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225179/
https://ncbi.nlm.nih.gov/pubmed/24925693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semarthrit.2014.05.007
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