Rad7 E3 Ubiquitin Ligase Attenuates Polyubiquitylation of Rpn10 and Dsk2 Following DNA Damage in Saccharomyces cerevisiae

During Nucleotide Excision Repair (NER) in the yeast S. cerevisiae, ubiquitylation of Rad4 is carried out by the E3 ubiquitin ligase that includes Rad7-Elc1-Cul3 and is critical to optimal NER. Rad7 E3 activity targets Rad4 for degradation by the proteaseome but, in principle, could also trigger oth...

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Bibliografiska uppgifter
I publikationen:Adv Biol Chem
Huvudupphovsmän: Benoun, Joseph M., Lalimar-Cortez, Danielle, Valencia, Analila, Granda, Adriana, Moore, Destaye M., Kelson, Eric P., Fischhaber, Paula L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832922/
https://ncbi.nlm.nih.gov/pubmed/27092291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4236/abc.2015.57021
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