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The ubiquitin ligase Rsp5 is required for ribosome stability in Saccharomyces cerevisiae

Rsp5p is a conserved HECT-domain ubiquitin ligase with diverse roles in cellular physiology. Here we report a previously unknown role of Rsp5p in facilitating the stability of the cytoplasmic ribosome pool in budding yeast. Yeast strains carrying temperature-sensitive mutations in RSP5 showed a prog...

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Bibliografiska uppgifter
Huvudupphovsmän: Shcherbik, Natalia, Pestov, Dimitri G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153967/
https://ncbi.nlm.nih.gov/pubmed/21665996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2615311
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