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The ubiquitin ligase Rsp5 is required for ribosome stability in Saccharomyces cerevisiae
Rsp5p is a conserved HECT-domain ubiquitin ligase with diverse roles in cellular physiology. Here we report a previously unknown role of Rsp5p in facilitating the stability of the cytoplasmic ribosome pool in budding yeast. Yeast strains carrying temperature-sensitive mutations in RSP5 showed a prog...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3153967/ https://ncbi.nlm.nih.gov/pubmed/21665996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2615311 |
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