Using hydrogen deuterium exchange mass spectrometry to engineer optimized constructs for crystallization of protein complexes: Case study of PI4KIIIβ with Rab11

The ability of proteins to bind and interact with protein partners plays fundamental roles in many cellular contexts. X‐ray crystallography has been a powerful approach to understand protein‐protein interactions; however, a challenge in the crystallization of proteins and their complexes is the pres...

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Bibliographic Details
Published in:Protein Sci
Main Authors: Fowler, Melissa L., McPhail, Jacob A., Jenkins, Meredith L., Masson, Glenn R., Rutaganira, Florentine U., Shokat, Kevan M., Williams, Roger L., Burke, John E.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832280/
https://ncbi.nlm.nih.gov/pubmed/26756197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2879
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