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Mycobacteria-responsive sonic hedgehog signaling mediates programmed death-ligand 1- and prostaglandin E(2)-induced regulatory T cell expansion
CD4(+)CD25(+)FoxP3(+) regulatory T cells (Tregs) are exploited by mycobacteria to subvert the protective host immune responses. The Treg expansion in the periphery requires signaling by professional antigen presenting cells and in particularly dendritic cells (DC). However, precise molecular mechani...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4832185/ https://ncbi.nlm.nih.gov/pubmed/27080341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24193 |
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