NOD2-Nitric Oxide-responsive MicroRNA-146a Activates Sonic Hedgehog Signaling to Orchestrate Inflammatory Responses in Murine Model of Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) is a debilitating chronic inflammatory disorder of the intestine. The interactions between enteric bacteria and genetic susceptibilities are major contributors of IBD etiology. Although genetic variants with loss or gain of NOD2 functions have been linked to IBD susc...

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Detalhes bibliográficos
Main Authors: Ghorpade, Devram Sampat, Sinha, Akhuri Yash, Holla, Sahana, Singh, Vikas, Balaji, Kithiganahalli Narayanaswamy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829153/
https://ncbi.nlm.nih.gov/pubmed/24092752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.492496
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