Nitric Oxide and KLF4 Protein Epigenetically Modify Class II Transactivator to Repress Major Histocompatibility Complex II Expression during Mycobacterium bovis Bacillus Calmette-Guérin Infection

Pathogenic mycobacteria employ several immune evasion strategies such as inhibition of class II transactivator (CIITA) and MHC-II expression, to survive and persist in host macrophages. However, precise roles for specific signaling components executing down-regulation of CIITA/MHC-II have not been a...

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Main Authors: Ghorpade, Devram Sampat, Holla, Sahana, Sinha, Akhauri Yash, Alagesan, Senthil Kumar, Balaji, Kithiganahalli Narayanaswamy
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711323/
https://ncbi.nlm.nih.gov/pubmed/23733190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.472183
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