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Mycobacteria-responsive sonic hedgehog signaling mediates programmed death-ligand 1- and prostaglandin E(2)-induced regulatory T cell expansion
CD4(+)CD25(+)FoxP3(+) regulatory T cells (Tregs) are exploited by mycobacteria to subvert the protective host immune responses. The Treg expansion in the periphery requires signaling by professional antigen presenting cells and in particularly dendritic cells (DC). However, precise molecular mechani...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4832185/ https://ncbi.nlm.nih.gov/pubmed/27080341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24193 |
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