Mycobacteria-responsive sonic hedgehog signaling mediates programmed death-ligand 1- and prostaglandin E(2)-induced regulatory T cell expansion

CD4(+)CD25(+)FoxP3(+) regulatory T cells (Tregs) are exploited by mycobacteria to subvert the protective host immune responses. The Treg expansion in the periphery requires signaling by professional antigen presenting cells and in particularly dendritic cells (DC). However, precise molecular mechani...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Holla, Sahana, Stephen-Victor, Emmanuel, Prakhar, Praveen, Sharma, Meenu, Saha, Chaitrali, Udupa, Vibha, Kaveri, Srinivas V., Bayry, Jagadeesh, Balaji, Kithiganahalli Narayanaswamy
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832185/
https://ncbi.nlm.nih.gov/pubmed/27080341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24193
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