MicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturation

G protein-coupled receptor (GPCR) signalling, including that involving apelin (APLN) and its receptor APLNR, is known to be important in vascular development. How this ligand–receptor pair regulates the downstream signalling cascades in this context remains poorly understood. Here, we show that mice...

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Pubblicato in:Nat Commun
Autori principali: Papangeli, Irinna, Kim, Jongmin, Maier, Inna, Park, Saejeong, Lee, Aram, Kang, Yujung, Tanaka, Keiichiro, Khan, Omar F., Ju, Hyekyung, Kojima, Yoko, Red-Horse, Kristy, Anderson, Daniel G., Siekmann, Arndt F., Chun, Hyung J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832062/
https://ncbi.nlm.nih.gov/pubmed/27068353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11268
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