Restoration of Impaired Endothelial MEF2 Function Rescues Pulmonary Arterial Hypertension

BACKGROUND: Pulmonary arterial hypertension (PAH) is a progressive disease of the pulmonary arterioles, characterized by increased pulmonary arterial pressure and right ventricular failure. The etiology of PAH is complex, but aberrant proliferation of the pulmonary artery endothelial cells (PAECs) a...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Kim, Jongmin, Hwangbo, Cheol, Hu, Xiaoyue, Kang, Yujung, Papangeli, Irinna, Mehrotra, Devi, Park, Hyekyung, Ju, Hyekyung, McLean, Danielle L., Comhair, Suzy A., Erzurum, Serpil C., Chun, Hyung J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293354/
https://ncbi.nlm.nih.gov/pubmed/25336633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.013339
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