Endothelial Apelin-FGF Link Mediated by MicroRNAs 424 and 503 is Disrupted in Pulmonary Arterial Hypertension

Pulmonary arterial hypertension is characterized by vascular remodeling associated with obliteration of pulmonary arterioles and formation of plexiform lesions comprised of hyperproliferative endothelial and vascular smooth muscle cells. Here, we describe a novel, microRNA-dependent association betw...

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Detalhes bibliográficos
Main Authors: Kim, Jongmin, Kang, Yujung, Kojima, Yoko, Lighthouse, Janet K., Hu, Xiaoyue, Aldred, Micheala A., McLean, Danielle L., Park, Hyekyung, Comhair, Suzy A., Greif, Daniel M., Erzurum, Serpil C., Chun, Hyung J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540168/
https://ncbi.nlm.nih.gov/pubmed/23263626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3040
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