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Apelin/APJ Signaling is a Critical Regulator of Statin Effects in Vascular Endothelial Cells
OBJECTIVE: The endothelial response elicited by the G protein coupled receptor (GPCR) pathway involving apelin and APJ predict an overall vasoprotective effect. As the downstream endothelial targets of apelin/APJ signaling are also known to be targeted by statins (HMG-CoA reductase inhibitors) as po...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3495062/ https://ncbi.nlm.nih.gov/pubmed/22995518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300317 |
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