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Endothelial Apelin-FGF Link Mediated by MicroRNAs 424 and 503 is Disrupted in Pulmonary Arterial Hypertension

Pulmonary arterial hypertension is characterized by vascular remodeling associated with obliteration of pulmonary arterioles and formation of plexiform lesions comprised of hyperproliferative endothelial and vascular smooth muscle cells. Here, we describe a novel, microRNA-dependent association betw...

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Bibliografiske detaljer
Main Authors: Kim, Jongmin, Kang, Yujung, Kojima, Yoko, Lighthouse, Janet K., Hu, Xiaoyue, Aldred, Micheala A., McLean, Danielle L., Park, Hyekyung, Comhair, Suzy A., Greif, Daniel M., Erzurum, Serpil C., Chun, Hyung J.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540168/
https://ncbi.nlm.nih.gov/pubmed/23263626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3040
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