MicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturation

G protein-coupled receptor (GPCR) signalling, including that involving apelin (APLN) and its receptor APLNR, is known to be important in vascular development. How this ligand–receptor pair regulates the downstream signalling cascades in this context remains poorly understood. Here, we show that mice...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Papangeli, Irinna, Kim, Jongmin, Maier, Inna, Park, Saejeong, Lee, Aram, Kang, Yujung, Tanaka, Keiichiro, Khan, Omar F., Ju, Hyekyung, Kojima, Yoko, Red-Horse, Kristy, Anderson, Daniel G., Siekmann, Arndt F., Chun, Hyung J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832062/
https://ncbi.nlm.nih.gov/pubmed/27068353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11268
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