Mechanisms of the inhibition of reverse transcription by antisense oligonucleotides.
We have demonstrated that the synthesis of cDNA by avian myeloblastosis virus and Moloney murine leukemia virus reverse transcriptases can be prevented by oligonucleotides bound to the RNA template approximately 100 nucleotides remote from the 3' end of the primer. The RNA was truncated at the level...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48320/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1370586/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.2.768 |
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