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Mechanisms of the inhibition of reverse transcription by antisense oligonucleotides.

We have demonstrated that the synthesis of cDNA by avian myeloblastosis virus and Moloney murine leukemia virus reverse transcriptases can be prevented by oligonucleotides bound to the RNA template approximately 100 nucleotides remote from the 3' end of the primer. The RNA was truncated at the...

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Autors principals: Boiziau, C, Thuong, N T, Toulmé, J J
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC48320/
https://ncbi.nlm.nih.gov/pubmed/1370586
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