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Inhibition of gene expression by triple helix-directed DNA cross-linking at specific sites.

Synthetic oligodeoxynucleotides represent promising tools for gene inhibition in live systems. Triple helix-forming oligonucleotides, which bind to double-stranded DNA, are of special interest since they are targeted to the gene itself rather than to its mRNA product, as in the antisense strategy. T...

詳細記述

保存先:
書誌詳細
主要な著者: Grigoriev, M, Praseuth, D, Guieysse, A L, Robin, P, Thuong, N T, Hélène, C, Harel-Bellan, A
フォーマット: Artigo
言語:Inglês
出版事項: 1993
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC46328/
https://ncbi.nlm.nih.gov/pubmed/8475098
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