Inhibition of gene expression by triple helix-directed DNA cross-linking at specific sites.

Synthetic oligodeoxynucleotides represent promising tools for gene inhibition in live systems. Triple helix-forming oligonucleotides, which bind to double-stranded DNA, are of special interest since they are targeted to the gene itself rather than to its mRNA product, as in the antisense strategy. T...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Grigoriev, M, Praseuth, D, Guieysse, A L, Robin, P, Thuong, N T, Hélène, C, Harel-Bellan, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46328/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8475098/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.8.3501
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