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Syntheses and biological evaluation of new cephalosporin-oxazolidinone conjugates()

Two cephalosporin-oxazolidinone conjugates were synthesized by incorporation of a carbamate linker at the 3′-position of the cephalosporin. These compounds show stability in aqueous media until specifically activated by a β-lactamase, and retain antibacterial activities profiles reflecting both the...

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Bibliografiska uppgifter
I publikationen:Medchemcomm
Huvudupphovsmän: Yan, Shanshan, Miller, Marvin J., Wencewicz, Timothy A., Möollmann, Ute
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831628/
https://ncbi.nlm.nih.gov/pubmed/27087912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C0MD00015A
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