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Trihydroxamate Siderophore-Fluoroquinolone Conjugates are Selective Sideromycin Antibiotics that Target Staphylococcus aureus

Siderophores are multidentate iron(III) chelators used by bacteria for iron assimilation. Sideromycins, also called siderophore-antibiotic conjugates, are a unique subset of siderophores that enter bacterial cells via siderophore uptake pathways and deliver the toxic antibiotic in a ‘Trojan Horse’ f...

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Bibliografski detalji
Glavni autori: Wencewicz, Timothy A., Long, Timothy E., Möllmann, Ute, Miller, Marvin J.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633530/
https://ncbi.nlm.nih.gov/pubmed/23350642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc300610f
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