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Presynaptic, release‐regulating mGlu(2)‐preferring and mGlu(3)‐preferring autoreceptors in CNS: pharmacological profiles and functional roles in demyelinating disease
BACKGROUND AND PURPOSE: Presynaptic, release‐regulating metabotropic glutamate 2 and 3 (mGlu(2/3)) autoreceptors exist in the CNS. They represent suitable targets for therapeutic approaches to central diseases that are typified by hyperglutamatergicity. The availability of specific ligands able to d...
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Publicado en: | Br J Pharmacol |
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Autores principales: | , , , , , , , , |
Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4831303/ https://ncbi.nlm.nih.gov/pubmed/26791341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13442 |
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