Presynaptic mGlu1 Receptors Control GABA(B) Receptors in an Antagonist-Like Manner in Mouse Cortical GABAergic and Glutamatergic Nerve Endings

Mouse cortical GABAergic synaptosomes possess presynaptic inhibitory GABA(B) autoreceptors. Accordingly, (±)baclofen (3 μM) inhibits in a CGP53423-sensitive manner the 12 mM KCl-evoked release of preloaded [(3)H]GABA. Differently, the existence of presynaptic release-regulating metabotropic glutamat...

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Bibliografiska uppgifter
I publikationen:Front Mol Neurosci
Huvudupphovsmän: Vergassola, Matteo, Olivero, Guendalina, Cisani, Francesca, Usai, Cesare, Bossi, Simone, Puliti, Aldamaria, Pittaluga, Anna
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2018
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153310/
https://ncbi.nlm.nih.gov/pubmed/30279647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00324
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