Presynaptic, release‐regulating mGlu(2)‐preferring and mGlu(3)‐preferring autoreceptors in CNS: pharmacological profiles and functional roles in demyelinating disease

BACKGROUND AND PURPOSE: Presynaptic, release‐regulating metabotropic glutamate 2 and 3 (mGlu(2/3)) autoreceptors exist in the CNS. They represent suitable targets for therapeutic approaches to central diseases that are typified by hyperglutamatergicity. The availability of specific ligands able to d...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Di Prisco, Silvia, Merega, Elisa, Bonfiglio, Tommaso, Olivero, Guendalina, Cervetto, Chiara, Grilli, Massimo, Usai, Cesare, Marchi, Mario, Pittaluga, Anna
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831303/
https://ncbi.nlm.nih.gov/pubmed/26791341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13442
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