Presynaptic, release‐regulating mGlu(2)‐preferring and mGlu(3)‐preferring autoreceptors in CNS: pharmacological profiles and functional roles in demyelinating disease

BACKGROUND AND PURPOSE: Presynaptic, release‐regulating metabotropic glutamate 2 and 3 (mGlu(2/3)) autoreceptors exist in the CNS. They represent suitable targets for therapeutic approaches to central diseases that are typified by hyperglutamatergicity. The availability of specific ligands able to d...

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Dettagli Bibliografici
Pubblicato in:Br J Pharmacol
Autori principali: Di Prisco, Silvia, Merega, Elisa, Bonfiglio, Tommaso, Olivero, Guendalina, Cervetto, Chiara, Grilli, Massimo, Usai, Cesare, Marchi, Mario, Pittaluga, Anna
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831303/
https://ncbi.nlm.nih.gov/pubmed/26791341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13442
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