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Presynaptic, release‐regulating mGlu(2)‐preferring and mGlu(3)‐preferring autoreceptors in CNS: pharmacological profiles and functional roles in demyelinating disease

BACKGROUND AND PURPOSE: Presynaptic, release‐regulating metabotropic glutamate 2 and 3 (mGlu(2/3)) autoreceptors exist in the CNS. They represent suitable targets for therapeutic approaches to central diseases that are typified by hyperglutamatergicity. The availability of specific ligands able to d...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Pharmacol
Prif Awduron: Di Prisco, Silvia, Merega, Elisa, Bonfiglio, Tommaso, Olivero, Guendalina, Cervetto, Chiara, Grilli, Massimo, Usai, Cesare, Marchi, Mario, Pittaluga, Anna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831303/
https://ncbi.nlm.nih.gov/pubmed/26791341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13442
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