Hsd11b2 HAPLOINSUFFICIENCY IN MICE CAUSES SALT-SENSITIVITY OF BLOOD PRESSURE

Salt-sensitivity of blood pressure is an independent risk factor for cardiovascular morbidity. Mechanistically, abnormal mineralocorticoid action and sub-clinical renal impairment may blunt the natriuretic response to high sodium intake, causing blood pressure to rise. 11β-hydroxysteroid dehydrogena...

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Publicat a:Hypertension
Autors principals: Bailey, Matthew A., Craigie, Eilidh, Livingstone, Dawn E.W., Kotelevtsev, Yuri V., Al-Dujaili, Emad A.S., Kenyon, Christopher J., Mullins, John J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830399/
https://ncbi.nlm.nih.gov/pubmed/21282561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.110.163782
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