Mineralocorticoid Excess or Glucocorticoid Insufficiency: Renal and Metabolic Phenotypes in a Rat Hsd11b2 Knockout Model

Obesity and hypertension are 2 major health issues of the 21st century. The syndrome of apparent mineralocorticoid excess is caused by deficiency of 11β-hydroxysteroid dehydrogenase type 2 (Hsd11b2), which normally inactivates glucocorticoids, rendering the mineralocorticoid receptor aldosterone–spe...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Mullins, Linda J., Kenyon, Christopher J., Bailey, Matthew A., Conway, Bryan R., Diaz, Mary E., Mullins, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott, Williams & Wilkins 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847935/
https://ncbi.nlm.nih.gov/pubmed/26077568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05262
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