Wordt geladen...

Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic Rheb degradation

As traditional antidepressants act only after weeks/months, the discovery that ketamine, an antagonist of glutamate/NMDA receptors, elicits antidepressant actions in hours has been transformative. Its mechanism of action has been elusive, though enhanced mTOR signaling is a major feature. We report...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Mol Psychiatry
Hoofdauteurs: Harraz, Maged M., Tyagi, Richa, Cortés, Pedro, Snyder, Solomon H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830355/
https://ncbi.nlm.nih.gov/pubmed/26782056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.211
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!