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Antidepressant Actions of Ketamine Mediated by the Mechanistic Target of Rapamycin, Nitric Oxide, and Rheb

The weeks/months it takes for traditional antidepressants to act pose an obstacle in the management of depression. Ketamine’s prompt and sustained antidepressant effects constitute a major advance. Multiple studies implicate glutamatergic signaling to protein synthesis machinery and synapse formatio...

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Detalhes bibliográficos
Publicado no:Neurotherapeutics
Main Authors: Harraz, Maged M., Snyder, Solomon H.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509634/
https://ncbi.nlm.nih.gov/pubmed/28612328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-017-0540-0
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