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The Dark Side of Cell Signaling: Positive Roles for Negative Regulators

Cell signaling is dominated by analyzing positive responses to stimuli. Signal activation is balanced by negative regulators that are generally considered to terminate signaling. Rather than exerting only negative effects, however, many such regulators play important roles in enhancing cell-signalin...

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Détails bibliographiques
Publié dans:Cell
Auteurs principaux: Lemmon, Mark A., Freed, Daniel M., Schlessinger, Joseph, Kiyatkin, Anatoly
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830124/
https://ncbi.nlm.nih.gov/pubmed/26967284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.02.047
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