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Exiting the dark side: A vital role for Caspase-3 in Yap signaling

Caspase-3 is known to play a critical function in the process of apoptosis. Recently, we have discovered a non-apoptotic role of Caspase-3 as a key regulator of cell proliferation and organ size. Caspase-3 cleaves α-Catenin, which sequesters Yes-associated protein 1 (Yap1) in the cytoplasm, thus fac...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Yosefzon, Yahav, Fuchs, Yaron
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149913/
https://ncbi.nlm.nih.gov/pubmed/30250929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1494947
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