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The dark side of Toll-like receptor signaling: TLR9 activation limits the efficacy cancer radiotherapy

Radiation therapy is potentially immunogenic yet it rarely generates long-term antitumor effects. We have recently demonstrated that Toll-like receptor 9 (TLR9) jump-starts the signal transduction and activator of transcription 3 (STAT3)-dependent vascularization and regrowth of tumors that recur up...

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Detalhes bibliográficos
Main Authors: Kortylewski, Marcin, Pal, Sumanta K
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203530/
https://ncbi.nlm.nih.gov/pubmed/25340001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.27894
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