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Push and release: TLR9 activation plus STAT3 blockade for systemic antitumor immunity

Proper immunostimulation (“push”) and immune checkpoint blockade (“release”) are both critical for the efficacy of anticancer immunotherapy. We have recently shown that activating Toll-like receptor 9 (TLR9) while specifically blocking signal transducer and activator of transcription 3 (STAT3) in le...

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Hlavní autoři: Kortylewski, Marcin, Kuo, Ya-Huei
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006856/
https://ncbi.nlm.nih.gov/pubmed/24800162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.27441
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