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The Dark Side of Cell Signaling: Positive Roles for Negative Regulators

Cell signaling is dominated by analyzing positive responses to stimuli. Signal activation is balanced by negative regulators that are generally considered to terminate signaling. Rather than exerting only negative effects, however, many such regulators play important roles in enhancing cell-signalin...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Lemmon, Mark A., Freed, Daniel M., Schlessinger, Joseph, Kiyatkin, Anatoly
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830124/
https://ncbi.nlm.nih.gov/pubmed/26967284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.02.047
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