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Potential clinical implications of recent MMP inhibitor design strategies

Analysis of MMP expression profiles in various pathologies correlated their presence in promoting disease progression. Drugs were designed to inhibit MMPs in an extreme manner by chelating the active site zinc ion. This approach did not distinguish between the 24 members of the MMP family and had de...

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Detalhes bibliográficos
Publicado no:Expert Rev Proteomics
Main Authors: Amar, Sabrina, Fields, Gregg B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829401/
https://ncbi.nlm.nih.gov/pubmed/26174966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14789450.2015.1069190
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