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New strategies for targeting matrix metalloproteinases
The development of matrix metalloproteinase (MMP) inhibitors has often been frustrated by a lack of specificity and subsequent off-target effects. More recently, inhibitor design has considered secondary binding sites (exosites) to improve specificity. Small molecules and peptides have been develope...
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| Udgivet i: | Matrix Biol |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4466128/ https://ncbi.nlm.nih.gov/pubmed/25595836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2015.01.002 |
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