Characterization and regulation of MT1-MMP cell surface-associated activity

Quantitative assessment of MT1-MMP cell surface-associated proteolytic activity remains undefined. Presently, MT1-MMP was stably expressed and a cell-based FRET assay developed to quantify activity towards synthetic collagen-model triple-helices. To estimate the importance of cell surface localizati...

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Bibliographic Details
Published in:Chem Biol Drug Des
Main Authors: Pahwa, Sonia, Bhowmick, Manishabrata, Amar, Sabrina, Cao, Jian, Strongin, Alex Y., Fridman, Rafael, Weiss, Stephen J., Fields, Gregg B.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536371/
https://ncbi.nlm.nih.gov/pubmed/30480376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.13450
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