HuR antagonizes the effect of an intronic pyrimidine-rich sequence in regulating WT1 +/−KTS isoforms

WT1 + KTS and −KTS isoforms only differ in 3 amino acids in protein sequence but show significant functional difference. The +/−KTS isoforms were generated by alternative usage of 2 adjacent 5’ splice sites at RNA level, however, how these 2 isoforms are regulated is still elusive. Here we report th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Li, Hui, Hou, Shuai, Hao, Tian, Azam, Sikandar, Liu, Caigang, Shi, Lei, Lei, Haixin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829285/
https://ncbi.nlm.nih.gov/pubmed/26512748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1102831
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados