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The Wilms’ tumor 1 (WT1) gene (+KTS isoform) functions with a CTE to enhance translation from an unspliced RNA with a retained intron

The Wilms’ tumor 1 (WT1) gene plays an important role in mammalian urogenital development, and dysregulation of this gene is observed in many human cancers. Alternative splicing of WT1 RNA leads to the expression of two major protein isoforms, WT1(+KTS) and WT1(−KTS). Whereas WT1(−KTS) acts as a tra...

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Hlavní autoři: Bor, Yeou, Swartz, Jennifer, Morrison, Avril, Rekosh, David, Ladomery, Michael, Hammarskjöld, Marie-Louise
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482480/
https://ncbi.nlm.nih.gov/pubmed/16738405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1402306
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