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The Wilms’ tumor 1 (WT1) gene (+KTS isoform) functions with a CTE to enhance translation from an unspliced RNA with a retained intron

The Wilms’ tumor 1 (WT1) gene plays an important role in mammalian urogenital development, and dysregulation of this gene is observed in many human cancers. Alternative splicing of WT1 RNA leads to the expression of two major protein isoforms, WT1(+KTS) and WT1(−KTS). Whereas WT1(−KTS) acts as a tra...

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Autors principals: Bor, Yeou, Swartz, Jennifer, Morrison, Avril, Rekosh, David, Ladomery, Michael, Hammarskjöld, Marie-Louise
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482480/
https://ncbi.nlm.nih.gov/pubmed/16738405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1402306
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