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Modulation of Macrophage Polarization and HMGB1-TLR2/TLR4 Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice

The aim of this study was to investigate the role of macrophage polarization in aging heart. Macrophage differentiation is pathogenically linked to many inflammatory and immune disorders. It is often preceded by myocardial inflammation, which is characterized by increased cardiac damage and pro-infl...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Karuppagounder, Vengadeshprabhu, Giridharan, Vijayasree V., Arumugam, Somasundaram, Sreedhar, Remya, Palaniyandi, Suresh S., Krishnamurthy, Prasanna, Quevedo, Joao, Watanabe, Kenichi, Konishi, Tetsuya, Thandavarayan, Rajarajan A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829159/
https://ncbi.nlm.nih.gov/pubmed/27070323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152922
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