CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice

CALHM1 is a cell surface calcium channel expressed in cerebral neurons. CALHM1 function in the brain remains unknown, but recent results showed that neuronal CALHM1 controls intracellular calcium signaling and cell excitability, two mechanisms required for synaptic function. Here, we describe the ge...

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Publicat a:Sci Rep
Autors principals: Vingtdeux, Valérie, Chang, Eric H., Frattini, Stephen A., Zhao, Haitian, Chandakkar, Pallavi, Adrien, Leslie, Strohl, Joshua J., Gibson, Elizabeth L., Ohmoto, Makoto, Matsumoto, Ichiro, Huerta, Patricio T., Marambaud, Philippe
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828655/
https://ncbi.nlm.nih.gov/pubmed/27066908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24250
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