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Calpastatin inhibits motor neuron death and increases survival of hSOD1(G93A) mice
Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease with a poorly understood cause and no effective treatment. Given that calpains mediate neurodegeneration in other pathological states and are abnormally activated in ALS, we investigated the possible ameliorative effects of in...
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| Publicado no: | J Neurochem |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4828294/ https://ncbi.nlm.nih.gov/pubmed/26756888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13536 |
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