Tempol Moderately Extends Survival in a hSOD1(G93A) ALS Rat Model by Inhibiting Neuronal Cell Loss, Oxidative Damage and Levels of Non-Native hSOD1(G93A) Forms

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive dysfunction and death of motor neurons by mechanisms that remain unclear. Evidence indicates that oxidative mechanisms contribute to ALS pathology, but classical antioxidants have not performed...

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Detalhes bibliográficos
Main Authors: Linares, Edlaine, Seixas, Luciana V., dos Prazeres, Janaina N., Ladd, Fernando V. L., Ladd, Aliny A. B. L., Coppi, Antonio A., Augusto, Ohara
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566093/
https://ncbi.nlm.nih.gov/pubmed/23405225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055868
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