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Effects of RAGE inhibition on the progression of the disease in hSOD1(G93A) ALS mice

Astrocytes play a key role in the progression of amyotrophic lateral sclerosis (ALS) by actively inducing the degeneration of motor neurons. Motor neurons isolated from receptor for advanced glycation end products (RAGE)‐knockout mice are resistant to the neurotoxic signal derived from ALS‐astrocyte...

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Foilsithe in:Pharmacol Res Perspect
Main Authors: Liu, Liping, Killoy, Kelby M., Vargas, Marcelo R., Yamamoto, Yasuhiko, Pehar, Mariana
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415959/
https://ncbi.nlm.nih.gov/pubmed/32776498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.636
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