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Effects of RAGE inhibition on the progression of the disease in hSOD1(G93A) ALS mice

Astrocytes play a key role in the progression of amyotrophic lateral sclerosis (ALS) by actively inducing the degeneration of motor neurons. Motor neurons isolated from receptor for advanced glycation end products (RAGE)‐knockout mice are resistant to the neurotoxic signal derived from ALS‐astrocyte...

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Bibliografiske detaljer
Udgivet i:Pharmacol Res Perspect
Main Authors: Liu, Liping, Killoy, Kelby M., Vargas, Marcelo R., Yamamoto, Yasuhiko, Pehar, Mariana
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415959/
https://ncbi.nlm.nih.gov/pubmed/32776498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.636
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