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Effects of RAGE inhibition on the progression of the disease in hSOD1(G93A) ALS mice
Astrocytes play a key role in the progression of amyotrophic lateral sclerosis (ALS) by actively inducing the degeneration of motor neurons. Motor neurons isolated from receptor for advanced glycation end products (RAGE)‐knockout mice are resistant to the neurotoxic signal derived from ALS‐astrocyte...
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| Publicado no: | Pharmacol Res Perspect |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7415959/ https://ncbi.nlm.nih.gov/pubmed/32776498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.636 |
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