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Decreased glutathione levels cause overt motor neuron degeneration in hSOD1(WT) overexpressing mice
Mutations in Cu/Zn-superoxide dismutase (SOD1) cause familial forms of amyotrophic lateral sclerosis (ALS), a fatal disorder characterized by the progressive loss of motor neurons. Several lines of evidence have shown that SOD1 mutations cause ALS through a gain of a toxic function that remains to b...
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| Publicado no: | Exp Neurol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5849514/ https://ncbi.nlm.nih.gov/pubmed/29307609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2018.01.004 |
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