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Soluble IgM links apoptosis to complement activation in early alcoholic liver disease in mice
BACKGROUND: Ethanol feeding in mice activates complement via C1q binding to apoptotic cells in the liver; complement contributes to ethanol-induced inflammation and injury. Despite the critical role of C1q in ethanol-induced injury, the mechanism by which ethanol activates C1q remains poorly underst...
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| Pubblicato in: | Mol Immunol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4828291/ https://ncbi.nlm.nih.gov/pubmed/26922040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2016.02.008 |
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