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Complement Factor D protects mice from ethanol-induced inflammation and liver injury

Complement plays a crucial role in microbial defense and clearance of apoptotic cells. Emerging evidence suggests complement is an important contributor to alcoholic liver disease. While complement component 1, Q subcomponent (C1q)-dependent complement activation contributes to ethanol-induced liver...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: McCullough, Rebecca L., McMullen, Megan R., Sheehan, Megan M., Poulsen, Kyle L., Roychowdhury, Sanjoy, Chiang, Dian J., Pritchard, Michele T., Caballeria, Juan, Nagy, Laura E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109707/
https://ncbi.nlm.nih.gov/pubmed/29597356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00334.2017
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