Differential contribution of complement receptor C5aR in myeloid and non-myeloid cells in chronic ethanol-induced liver injury in mice

BACKGROUND: Complement is implicated in the development of alcoholic liver disease. C3 and C5 contribute to ethanol-induced liver injury; however, the role of C5a receptor (C5aR) on myeloid and non-myeloid cells to progression of injury is not known. METHODS: C57BL/6 (WT), global C5aR−/−, myeloid-sp...

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Publicado no:Mol Immunol
Main Authors: McCullough, Rebecca L, McMullen, Megan R, Das, Dola, Roychowdhury, Sanjoy, Strainic, Michael G., Medof, M. Edward, Nagy, Laura E
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939119/
https://ncbi.nlm.nih.gov/pubmed/27280845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2016.05.006
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