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Inhibition of apoptosis protects mice from ethanol-mediated acceleration of early markers of CCl(4)-induced fibrosis but not steatosis or inflammation
BACKGROUND: Correlative evidence indicates that apoptosis is associated with the progression of alcoholic liver disease. If apoptosis contributes to ethanol-induced steatohepatitis and/or fibrosis, then mice deficient in Bid, a key pro-apoptotic Bcl-2 family member, or mice treated with a pan-caspas...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337974/ https://ncbi.nlm.nih.gov/pubmed/22273278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2011.01720.x |
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