Adenosine 2A Receptor Antagonist Prevented and Reversed Liver Fibrosis in a Mouse Model of Ethanol-Exacerbated Liver Fibrosis

The effect of moderate alcohol consumption on liver fibrosis is not well understood, but evidence suggests that adenosine may play a role in mediating the effects of moderate ethanol on tissue injury. Ethanol increases the concentration of adenosine in the liver. Adenosine 2A receptor (A2AR) activat...

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Main Authors: Chiang, Dian J., Roychowdhury, Sanjoy, Bush, Katelyn, McMullen, Megan R., Pisano, Sorana, Niese, Kathryn, Olman, Mitchell A., Pritchard, Michele T., Nagy, Laura E.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715448/
https://ncbi.nlm.nih.gov/pubmed/23874883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069114
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