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In the absence of its cytosolic domain, the CD28 molecule still contributes to T cell activation
The CD28 costimulatory receptor has a pivotal role in T cell biology as this molecule amplifies T cell receptor (TCR) signals to provide an efficient immune T cell response. There is a large debate about how CD28 mediates these signals. Here, we designed a CD28 gene-targeted knock-in mouse strain la...
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| Publicado no: | Cell Mol Life Sci |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Basel
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4826669/ https://ncbi.nlm.nih.gov/pubmed/25725801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-015-1873-7 |
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