In the absence of its cytosolic domain, the CD28 molecule still contributes to T cell activation

The CD28 costimulatory receptor has a pivotal role in T cell biology as this molecule amplifies T cell receptor (TCR) signals to provide an efficient immune T cell response. There is a large debate about how CD28 mediates these signals. Here, we designed a CD28 gene-targeted knock-in mouse strain la...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Mol Life Sci
Main Authors: Morin, Stéphanie O., Giroux, Valentin, Favre, Cédric, Bechah, Yassina, Auphan-Anezin, Nathalie, Roncagalli, Romain, Mège, Jean-Louis, Olive, Daniel, Malissen, Marie, Nunès, Jacques A.
Format: Artigo
Jezik:Inglês
Izdano: Springer Basel 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826669/
https://ncbi.nlm.nih.gov/pubmed/25725801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-015-1873-7
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